The Zhou group uses theory, computation, and experiment to address a range of topics in molecular and cellular biophysics. Four main areas are: (1) thermodynamic and dynamic properties of phase-separated biomolecular condensates; (2) membrane association and binding kinetics of intrinsically disordered proteins; (3) structures and pathways of the self-assemblies of amyloid-β and other amyloidogenic proteins; and (4) functional mechanisms of glutamate-receptor ion channels.
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Hot Publication Our evaluation of AlphaFold as a landmark published in Faculty Reviews
Grants The Zhou group is supported by grants from the National Institutes of Health.